OCEANUS SEMINAR SERIES | Cristina Velasco | 25 Nov  | 11h30


Title: The long-chain fatty acid receptors FFA1 and FFA4 are involved in food intake regulation in fish brain


Name: Cristina Velasco


Free fatty acids receptors are widely expressed in various tissues and contribute to important physiological processes. In mammals, the presence of these receptors in brain regions has been related to their putative role as fatty acid sensors involved in the regulation of food intake and energy homeostasis. In fish, available studies support the presence of fatty acid-sensing mechanisms comparable to those described in mammals and based on fatty acid metabolism, mitochondrial activity and fatty acid transport. However, until the implementation of this study there was no evidence of the presence and function of FFARs in fish brain. This study evidence a fatty-acid sensing role for FFA1 and FFA4 in rainbow trout brain areas involved in the control of food intake.


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