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Research Team

Evolutionary Genomics and Bioinformatics

The research developed comprehends several distinct areas within the field of genetics, such as comparative genomics, molecular evolution and natural selection studies, toxicogenomics , microbial genomics, software development and bioinformatics, modeling of interactions protein/toxin, genetic diversity of toxic invasive species, conservation genetics and ecological studies in endemics or endangered species and wildlife trade and bushmeat genetics.

Principal Investigator

Team Leader

PhD in Biology. Head of the Evolutionary Genomics and Bioinformatics Research Team from CIIMAR, University of Porto. Was Scientific-Technical Director of the Matosinhos Environmental Center (CMIA) from the Câmara Municipal de Matosinhos.

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Research Projects

ATLANTIDA

BLUEandGREEN

BUSHRISK

CyanoTox

EXTRATOTECA

iCULTURE

IGNITE

INNOVMAR

JELLYFISHERIES

MarInfo

Ocean3R

SARDINOMICS

SENSORY-OMICS

SeXomics

SponBIODIV

SYMBIOMICS

UVNatP

XANTIFOUL

Team members

MSc Student

 I am studying for a master’s degree in Marine Ecology and Biological Oceanography (OBEM) in Aix-Marseille University in France, and I am currently working as an intern in the Evolutionary genomics and bioinformatics team at the CIIMAR. My work is focus on the characterization of the patterns of genetic structure of Paramuricea clavata at different spatial scales, in order to infer the underlying historical and contemporary processes with a focus on connectivity, genetic drift and local adaptation.

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MSc Student

Carla Santos graduated in 2013 in Biology by the Faculty of Sciences, University of Porto. Currently, she is finishing her master degree in Legal Medicine at the Institute of Biomedical Sciences Abel Salazar. She has done her master thesis with a BYT+ scholarship in the EGB group, with the title “Genes from the pseudoautosomal region (PAR1) of the mammalian X chromosome: synteny, phylogeny and selection.” which earned the award of Best 2019/2020 BYT+ Internship.

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Researcher

Cristiana Moreira is a Postdoctoral researcher and also a Principal Investigator in a FCT funded project CyanoTox – Assessment of cyanobacterial toxins in aquatic systems: environmental impacts and development of new methodologies for their early detection (Ref. PTDC/AAG-GLO/2137/2014). She received her degree in Aquatic Sciences in 2001 from ICBAS- University of Porto and her PhD in 2013 in Biology from FCUP-University of Porto. Her research interests focus on molecular biology, more specifically on the development of new tools for the early screening of cyanobacteria and cyanotoxins. She author 19 scientific publications in international journals.

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MSc Student
Human Resources

I have a bachelor in Biology by FCUP since 2021 and I am now doing a master’s degree on Applications in Biotechnology and Synthetic Biology, also in FCUP. My dissertation project is based on the study of African Bushmeat Markets and the risk of infectious diseases transmission.

Research Grant

Daniela Almeida graduated in Biology from the DBio-University of Aveiro (Portugal) in 2011 and obtained her Ph.D. in Biology (specialty of Evolutionary Genomics) from the FCUP-University of Porto (Portugal) in 2017. Her research interests focus on structural, functional and evolutionary genomics, ecotoxicogenomics and bioinformatics, more specifically on the role of protein-coding genes in the environmental adaptation of metazoans. She is the author of 5 scientific publications in international journals.

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PhD Student

Emanuel Maldonado is a Research Fellow at CIIMAR in the Evolutionary Genomics and Bioinformatics group since September of 2010. He obtained graduation and masters degree in Computer Science from FCUP in 2007 and 2009, respectively. The masters degree project was inclusively developed in CIIMAR. His main research interests focus on studying and developing bioinformatics software applications and pipelines, thus integrating the broad fields of informatics and biology in areas, such as omics (genomics, transcriptomics, etc) and evolutionary biology. He has (co-)authored 12 scientific publications in international journals.

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PhD Student

Postgraduate researcher with Biology and Biochemistry backgrounds. Involved in research mostly focused in animal adaptation and development, within cephalopods and fishes, and the potential implications of these factors in the organisms’ evolution.

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Researcher

Auxiliary Researcher funded by FCT at CIIMAR/FCUP. Majored in Pharmaceutical Sciences (1998) at Central University of Las Villas, Cuba-Spain. MSc. in Biochemistry from Medicine School “Dr. de Zarate Ruiz”, Cuba (2009). PhD in Biology from University of Porto (2013), Portugal. Postdoc at CIIMAR (2014-2017). I have specialized in non-conventional bioinformatic methods applied to functional genomics, molecular evolution, and drug discovery. Recently, my focus has been on leveraging machine learning, complex networks, and evolutionary algorithms to search and design peptide drugs from antimicrobial peptides.

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MSc Student

Hugo Moreno graduated in Biology in 2020 by the Faculty of Sciences, University of Porto. Currently he is a master´s student in Biodiversity, Genetics and Evolution at CIBIO. In the Evolutionary Genomics and Bioinformatics group at CIIMAR, he is developing his Master´s project on the evolution of endothermy. His main research interests are evolutionary biology, genetics and molecular evolution.

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Researcher

My research is involved in a conservation biology framework. I work mostly at the infra-specific level and at the interaction between ecology and evolutionary biology. I study marine habitat-forming species impacted by global change, with a focus on temperate corals struggling with anthropogenic climate change. I combine population genetics/genomics and ecology (field surveys, experiments) to address different topics, from recolonization history (Ledoux et al. 2018; 2021) to population biology (Ledoux et al. 2020; Gazulla et al. 2021), species delimitation (Coelho et al. 2023) and functioning of marine protected areas (Horaud et al. 2023).

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PhD Student

Joana Falcão graduated in Biology from the University of Coimbra in 2008 and completed an MSc degree in Ecology in March 2010.Her interest in ecology, close contact with estuaries, marine ecosystems, and coastal waters, always present throughout the graduation, allowed her to work as a grant researcher in several research projects, from benthic sharks to zooplankton, passing by estuaries and the open sea. In 2016 she joined the Coastal Systems and Ocean research group at MARE-IPLeiria. She currently holds an FCT doctoral grant and develops her work at MARE-IPLEIRIA, Marine and Environmental Sciences Centre-Polytechnic of Leiria, CIIMAR-Interdisciplinary Centre of Marine and Environmental Research, and IPMA-Portuguese Institute for Sea and Atmosphere. Her PhD project aims to address long term changes in jellyfish populations through the monetarization of populations of gelatinous organisms on the Portuguese coast and assist in predicting future abundance fluctuations of these organisms in a thermally changing ocean, trying to determine the mechanisms by which climate change interacts with them and their prey (zooplankton and fish larvae) while quantifying the effects of the blooms of these organisms on the ecosystem, their driving forces and potential consequences for the tourism, industry and fisheries sectors.

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Researcher

Assistant Professor at the Centre for Ecological Sciences – Indian Institute of Science, Bengaluru (India). Evolutionary biologist with a passion for venom research, his research focuses on unraveling the forces of natural selection that sculpt toxin molecular scaffolds in the animal kingdom.

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PhD Student

Leonildo dos Anjo Viagem graduated in Marine Biology and obtained his Master’s degree in Molecular and Microbial Biology by Faculty of Sciences and Technologies of the University of Algarve. He is currently a PhD candidate in the Evolutionary Genomics and Bioinformatics group at CIIMAR. His main research interests are related to genomic evolution of genes associated with food preferences in cephalopods and how this may relate to the microbiome.

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PhD Student

Liliana Silva graduated in Biochemistry in 2009 and obtained her Master degree in Biochemistry in 2014 by, the Faculty of Sciences of University of Porto. She is currently a PhD student in the Evolutionary Genomics and Bioinformatics group at CIIMAR. Her main research interests are related with evolution of sensorial systems and environmental adaptation.

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PhD student

Luana Ramos graduated in Biology in 2012 and obtained her master’s degree in Biodiversity, Genetics and Evolution in 2014, by the Faculty of Sciences of University of Porto. She did an ERASMUS+ internship at the Senckenberg Research Institute in Frankfurt, Germany in 2015 and is currently a PhD student in the Evolutionary Genomics and Bioinformatics group at CIIMAR. Her main research interests are population genetics, conservation, bioinformatics and evolutionary genomics. Her current work is focused on the evolution of reproductive traits in vertebrates.

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PhD student

Manuel Seixas is a Master in Biotechnology of Marine Resources at the School of Tourism and Technology of the Sea (ESTM) of the Polytechnic Institute of Leiria (IPLeiria). Currently, he is a PhD Student at CIIMAR focused on the analysis of genome and transcriptome of elasmobranchs.

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PhD student
Human Resources

Marco Simões has a master’s degree in Marine Resources Biotechnology by the School of Tourism and Maritime Technology-Polytechnic of Leiria. Over the last few years, he has developed research work in the areas of Molecular Biology and Genetic Engineering at Cetemares – MARE Polytechnic of Leiria, Peniche. He has used several molecular techniques in research with plants, fish pathogen detection, species identification and search of antibiotic resistance genes in environmental microorganisms, metagenomics, metabarcoding and evolutionary genetics. Currently he is a PhD student.

Researcher

Mohamed Emam is a Research assistant at CIIMAR in the Evolutionary Genomics and Bioinformatics group since February of 2018. He is a master student his research interests focus on studying a positive selection in mammalian related sequences and codon usage analysis in human metagenomics data.

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Researcher

My investigations feed on the interaction between the sciences of evolution and conservation biology. I am investigating the patterns of diversification within several groups of mammals through different scales, including phylogenetics / phylogeography / population genetics. The ultimate goal of my research is to increase knowledge on the evolutionary dynamics and ecology of heritage taxa and to produce DNA-based tools for the implementation of wildlife management protocols.

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PhD student

Ricardo Alexandre Barroso graduated in 2019 in Biology and obtained his master’s degree in Applications in Biotechnology and Synthetic Biology in 2021, by the Faculty of Sciences of University of Porto. Currently, he is a a PhD student in the Evolutionary Genomics and Bioinformatics research group at CIIMAR. His work is focused on the evolution and characterization of toxins from venomous marine invertebrates through the analysis of genomes, transcriptomes and proteomes, exploring their ecological role and biomedical potential. He has research experience in bioinformatics, virology and parasitology, both in academia and industry.

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PhD Student

Rita Mendes graduated in 2012 in Biological Sciences and Health by the University of Azores, completed her master’s degree in Biology and Water Quality Management in 2014 and her master’s degree in Environmental Contamination and Toxicology in 2017, both in the Univeristy of Porto. Currently, she is a PhD student at the Evolutionary Genomics and Bioinformatics group at CIIMAR. Her research interests focus on the study of cyanobacteria and related toxins, molecular biology, next-generation methods, and environmental toxicology, especially when applied to freshwater systems.

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Research Grant

I’m a molecular ecologist interested in diversity, ecology and evolution of fishes. My research is based on molecular approach such as population genetics, seascape genetics, phylogeography, omics science (transcriptome and genomics), and also in the development of wildlife forensic tools for law enforcement and trade monitoring purposes. My current research focuses on understanding the influence of oceanographic features on the genetic diversity and population structure mainly of pelagic sharks and billfishes.

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Researcher

Rute Fonseca is an Assistant Professor at the University of Copenhagen, Denmark. She received her degree in Biochemistry in 2000 and her PhD in Computational Chemistry in 20016 from University of Porto. Rute uses computational tools to study molecular evolution in a variety of organisms. My recent work involves exploring large-scale genomic information on both modern and ancient DNA data sets. I am particularly interested in protein function evolution and how this impacts phenotypes.

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Researcher

I am an evolutionary biologist, with expertise in ecology, life history evolution, population genetics, herpetology, conservation and evolutionary genomics. The central drive of my research is to integrate these disciplines to understand the evolution of reptilian biodiversity in all its forms, from molecules to populations, and to contribute to their conservation.  My current work focuses in elucidating adaptive patterns of mitogenome evolution. To answer this question I employ modern molecular statistical analysis using bioinformatics methods, to detect changes in selective constraints on mitochondria DNA protein coding regions throughout chelonian evolution.

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PhD student

In 2017, Tomás Rodrigues achieved his undergraduate degree in Biology from the Faculty of Sciences at the University of Porto. He went on to successfully complete his master’s degree in Biology and Water Quality Management in 2019, also at the Faculty of Sciences of the University of Porto. Seeking international academic enrichment, he participated in an international mobility program at the University of Murcia in 2020.
Currently, Tomás Rodrigues is taking his PhD within the Evolutionary Genomics and Bioinformatics group at CIIMAR. His academic pursuits are guided by a profound curiosity in several fields, including Proteomics, Transcriptomics, Genomics, Genetics, Molecular Biology, Cell Biology, Biogeography, and Ecology. His research is centered around harnessing the potential of cnidarians through an integrative molecular and omics-based approach.

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PhD Student

Currently I am PhD student at CIIMAR. After working in LEGE during my BSc and MSc in the identification and understanding of symbionts from marine organisms, I am now enrolled in the Sustainable animal nutrition and feed (SANFEED) doctoral program, from ICBAS-UP in partnership with FCT and Soja de Portugal. The main focus of research is the nutritional influence in of the gastrointestinal tract (GIT) microbiome from poultry for improvement of meat quality and animal welfare as well as human diet quality.

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Main publications

Comparative Genomics Reveals Insights into Avian Genome Evolution and Adaptation.

Zhang G., Antunes A., et al.

2014Science, 346(6215): 1311-1320
Evolution of separate predation- and defence-evoked venoms in carnivorous snails.

Dutertre S., Jin A., Vetter I., Hamilton B., Sunagar K., Lavergne V., Dutertre V., Fry B.G., Antunes A., Venter D., Alewood P., Lewis R.

2014Nature communications, 5: 3521
Pangolin genomes and the evolution of mammalian scales and immunity.

Choo SW, Antunes A, et al.

2016Genome Research, 26(10): 1312-1322
Adaptive patterns of mitogenome evolution are associated with the loss of shell scutes in turtles.

Escalona T., Weadick C.J., Antunes A.

2017Molecular Biology and Evolution, 34(10): 2522-2536
Olfactory receptor subgenomes linked with broad ecological adaptations in Sauropsida.

Khan I., Yang Z., Maldonado E., Li C., Zhang G., Gilbert M.T.P., Jarvis E.D., O'Brien S.J., Johnson W.E., Antunes A.

2015Molecular Biology and Evolution, 32(11): 2832-2843
Genomic Legacy of the African Cheetah, Acinonyx jubatus.

Dobrynin P, Antunes A, et al.

2015Genome Biology, 16(1): 277
Evolution of CRISPs associated with toxicoferan-reptilian venom and mammalian reproduction.

Sunagar K., Johnson W.E., O'Brien S.J., Vasconcelos V., Antunes A.

2012Molecular Biology and Evolution, 29(7): 1807-1822
Fish lateral line innovation: insights into the evolutionary genomic dynamics of a unique mechanosensory organ.

Philip S., Machado J.P., Maldonado E., Vasconcelos V., O'Brien S.J., Johnson W.E., Antunes A.

2012Molecular Biology and Evolution, 29(12): 3887-3898
The evolutionary dynamics of Lion Panthera leo revealed by host and viral population genomics.

Antunes A., Troyer J.L., et al.

2008PLoS Genetics, 4(11): e1000251