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NUTRITION AND IMMUNOBIOLOGY

Principal Investigator:
Aires Oliva Teles

Through the improvement of cost-effective aquafeeds, NUTRIMU aims at maximizing fish growth performance and feed utilization, while minimizing environmental impact and cost of feeding, reducing chemicals as prophylactic agents use in aquaculture, and decreasing mortalities due to opportunistic pathogens. Attention is also given to nutritional strategies for improving animal welfare, gut integrity and immune status, thus reducing fish susceptibility to diseases and stressful rearing conditions.

NUTRIMU also aims to contribute for deeper insights on fish nutrient requirements, metabolic utilization of nutrients, nutrients-innate immune system interaction and neuroendocrine-immune interactions, therefore gaining basic information regarding physiological aspects of comparative animal nutrition and immunobiology. This research team also seeks to study potential ingredients for use in aquafeeds, potential use of functional ingredients, and gut microbiota-nutrients interaction, thus contributing for scientific sound improvement of fish feeds and fish health.

Main research activities are mainly directed towards the following topics: Protein and amino acid requirements; Carbohydrate and lipids utilization and metabolism; Evaluation of feedstuffs alternative to fish meal and fish oil; Utilization of functional ingredients in aquafeeds; Nutrition and gut microbiology; Nutritional immunobiology; Host/pathogen and neuroendocrine/immune interactions.

Publications Highlights

Azeredo R., Machado M., Afonso A., Fierro-Castro C., Reyes-Lopez F., Tort L., Gesto M., Conde-Sieira M., Míguez J.M., Soengas J.L., Kreuz E., Wuertz S., Peres H., Oliva-Teles A., Costas B. 2017. Neuroendocrine and immune responses to inflammation engaged different fates following tryptophan or methionine treatment: tales from a teleost model. Frontiers in Immunology, section Nutritional Immunology, 8: 1226.

Couto A., Enes P., Oliva-Teles A., Peres H. 2017. Nutritional value of whole cereal meals in diets for juvenile European sea bass (Dicentrarchus labrax). Aquaculture, 473:128-134.

Oliva-Teles A., Peres H., Kaushik S. 2017. Excess dietary arginine does not improve utilization of plant-based aquafeeds in sea bream juveniles. Aquaculture, 479:690-695.

Pereira A., Carvalho A.P., Cruz C., Saraiva, A. 2017. Histopathological changes and zootechnical performance in juvenile zebrafish (Danio rerio) under chronic exposure to nitrate. Aquaculture, 473: 197-205.

Rocha S., Rangel L.F., Castro R., Severino R. Azevedo C., Santos M.J., Casal G. 2016. Ultrastructure and phylogeny of Ceratomyxa diplodae Lubat et al. 1989 sensu Sitjà-Bobadilla & Álvarez-Pellitero, 1993 (Myxosporea: Ceratomyxidae), from the gall bladder of the European seabass Dicentrarchus labrax (Teleostei: Moronidae). Diseases of Aquatic Organisms 121: 117-128.

Projects